🧫
Myricanol treatment in HFD-induced hyperlipidemic C57BL/6J mice
active
experiment
Created: 2026-04-10T22:46:31
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-3f75797a-bb15-442f-9881-f
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:46:31.275142'} |
| p_value | None |
| protocol | 8-week HFD induction followed by 25-day treatment with myricanol (100 or 150 mg/kg) or rosiglitazone (0.78 mg/kg). Multi-omics analysis including Western blotting, metabolomics, 16S rRNA sequencing, R |
| effect_size | None |
| sample_size | None |
| source_pmid | 41520958 |
| extracted_at | 2026-04-10T15:46:31.270368 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Significant improvement in serum lipid profile, histopathological improvements in liver and adipose tissue, upregulation of beneficial metabolic genes |
| expected_outcomes | Reduction in serum lipid levels, decreased hepatic lipid accumulation, weight loss, and modulation of lipid metabolism pathways |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
33
Outgoing
35
0 supporting
0 contradicting
0 neutral
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