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Reproductive fitness analysis of psychiatric disorders in Swedish population

active
experiment Created: 2026-04-10T23:13:36 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-587cb56f-7bf6-4a63-ba7a-e
🧫 Experiment Protocol Clinicalproposed
N = 2.3 million individuals from 1950-1970 birth cohort in Sweden
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T23:13:36.208848'}
p_value< 10^-10
protocolPopulation-based analysis using Swedish Multi-Generation Register and Hospital Discharge Register. Measured fecundity of patients with psychiatric disorders and their unaffected siblings compared to g
effect_sizeFertility ratios ranging from 0.23-0.93 for affected individuals, 0.94-1.05 for siblings
sample_size2.3 million individuals from 1950-1970 birth cohort in Sweden
source_pmid23147713
extracted_at2026-04-10T16:13:36.206236
_schema_version1
experiment_typeclinical
success_criteriaStatistical significance in fertility ratio differences between affected individuals, siblings, and general population
expected_outcomesDetermine reproductive fitness patterns across psychiatric disorders and evaluate selection pressure on causal genetic variants
statistical_methodsFertility ratio calculations with corrections for demographic factors
📊 Evidence Profile
Evidence Balance
+0%
Certainty
15%
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