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IL-10 deficiency and VLC ceramide accumulation in inflammatory bowel disease

experiment Created: 2026-04-10 14:38:37 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-5eca67bb-dc0a-4b0e-86e1-1
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IL10
Metadata
experiment_typeanimal_model
protocolAnalysis of IL-10 deficient mice for inflammatory phenotypes, measurement of VLC ceramide levels, and assessment of inflammatory gene expression
expected_outcomesIL-10 deficient mice develop inflammatory bowel disease with increased VLC ceramide accumulation
success_criteriaDemonstration of causal link between IL-10 deficiency, VLC ceramide accumulation, and inflammatory disease
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T07:38:37.383934
source_pmid38383790
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T14:38:37.386490'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (7)
derives_from📄IL-10 constrains sphingolipid metabolism to limit inflammati100%
mentions📖IL10 — Interleukin 1080%
related📖IL10 — Interleukin 1072%
mentions📖researchers60%
related📖researchers54%
mentions📖move-brain-pd-nct0729927950%
mentions📖Intermediate Progenitor Cells44%

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