🧫

GWAS of plasma pTau181 in East Asian cohort

experiment Created: 2026-04-11 00:50:30 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-792473c3-ae88-48b9-9be1-b
🧫 Experiment Protocol Genetic Association
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Related Entities
KCNJ3, APOE
Metadata
experiment_typegenetic_association
protocolIllumina Asian Screening Array genotyping, same quality control procedures as pTau217 analysis
expected_outcomesIdentification of genetic loci associated with plasma pTau181 levels, replication of known associations in East Asian population
success_criteriagenome-wide significance (p < 5×10^-8)
sample_size1,972
statistical_methodsgenome-wide association analysis
p_valueNone
effect_sizeNone
extracted_at2026-04-10T17:50:30.814998
source_pmid41804841
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-11T00:50:30.854511'}
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Linked Artifacts (59)
produces🕸ent-gene-3aabf127 associated_with Alzheimer's_disease100%
mentions📖APOE-Expressing Astrocytes80%
mentions📖APOE Genotyping for Neurodegenerative Disease Risk Assessmen80%
mentions📖apoe80%
mentions📖APOE contributes to Alzheimer's disease by regulating b80%
mentions📖hypotheses-apoe-contributes-alzheimers-disease-regulat80%
mentions📖APOE Lipid Metabolism Pathway in Alzheimer's Disease80%
mentions📖ApoE (Apolipoprotein E)80%
related📖APOE-Expressing Astrocytes72%
related📖APOE Genotyping for Neurodegenerative Disease Risk Assessmen72%
related📖apoe72%
related📖APOE contributes to Alzheimer's disease by regulating b72%
related📖hypotheses-apoe-contributes-alzheimers-disease-regulat72%
related📖APOE Lipid Metabolism Pathway in Alzheimer's Disease72%
related📖ApoE (Apolipoprotein E)72%
mentions📖APOE Lipid Dysregulation Causal Chain in AD70%
mentions📖apoe-genotype-guided-prevention70%
mentions📖GWAS Findings Hub70%
mentions📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis70%
mentions📖KCNJ3 Gene70%
mentions📖KCNJ3 Protein70%
related📖APOE Lipid Dysregulation Causal Chain in AD63%
related📖apoe-genotype-guided-prevention63%
related📖GWAS Findings Hub63%
related📖GWAS Findings Hub: Alzheimer's and Parkinson's Dis63%
mentions📖Agitation in Alzheimer's Disease60%
mentions📖Alzheimer's Disease60%
mentions📖Alzheimer's Disease Genetic Variants60%
mentions📖Alzheimer's Disease vs Parkinson's Disease Compari60%
mentions📖APP Mutations in Alzheimer's Disease60%
mentions📖DLB, Parkinson's Disease, and Alzheimer's Disease:60%
mentions📖Early-Onset Alzheimer's Disease (EOAD)60%
mentions📖Investment Landscape: Alzheimer's Disease60%
mentions📖Preclinical Alzheimer's Disease60%
mentions📖Prodromal Alzheimer's Disease60%
mentions📖PSEN1 Mutations in Alzheimer's Disease60%
mentions📖PSEN2 Mutations in Alzheimer's Disease60%
mentions📖Sporadic vs Familial Alzheimer's Disease: Comprehensive60%
mentions📖TREM2 Variants in Alzheimer's Disease60%
related📖Alzheimer's Disease60%
related📖Agitation in Alzheimer's Disease54%
related📖Alzheimer's Disease54%
related📖Alzheimer's Disease Genetic Variants54%
related📖Alzheimer's Disease vs Parkinson's Disease Compari54%
related📖APP Mutations in Alzheimer's Disease54%
related📖DLB, Parkinson's Disease, and Alzheimer's Disease:54%
related📖Early-Onset Alzheimer's Disease (EOAD)54%
related📖Investment Landscape: Alzheimer's Disease54%
related📖Preclinical Alzheimer's Disease54%
related📖Prodromal Alzheimer's Disease54%
related📖PSEN1 Mutations in Alzheimer's Disease54%
related📖PSEN2 Mutations in Alzheimer's Disease54%
related📖Sporadic vs Familial Alzheimer's Disease: Comprehensive54%
related📖TREM2 Variants in Alzheimer's Disease54%
produces🕸GWAS associated_with Alzheimer's_disease50%
related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer33%
related📖KCNJ3 Gene33%
related📖KCNJ3 Protein33%
related🧫Summary-based Mendelian randomization analysis16%