🧫
Gestational haloperidol exposure effects on hippocampal gene expression
active
experiment
Created: 2026-04-10T22:32:39
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-7e7e92d9-da0a-4196-8ba9-9
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:32:39.348373'} |
| p_value | < 0.05 |
| protocol | Pregnant mice administered HAL (1 mg/kg/day), offspring hippocampus harvested for RNA-sequencing analysis, qPCR validation of selected genes, in silico prediction of miRNA regulation |
| effect_size | None |
| sample_size | None |
| source_pmid | 35859315 |
| extracted_at | 2026-04-10T15:32:39.344278 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Significant differential gene expression (P < 0.05 and q < 0.05), successful qPCR validation of RNA-seq findings |
| expected_outcomes | Altered gene expression patterns in hippocampus of HAL-exposed offspring, particularly changes in Nr3c1 expression and miR-137-3p regulation |
| statistical_methods | RNA-sequencing differential expression analysis with P < 0.05 and q < 0.05 thresholds |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
36
Outgoing
31
0 supporting
0 contradicting
0 neutral
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