🧫
Preinjury ACE-I/ARB exposure and outcomes in transfused trauma patients
active
experiment
Created: 2026-04-10T22:45:09
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-ce218d4c-2968-43a6-b813-a
🧫 Experiment Protocol
Clinicalproposed
N = 1013
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:45:09.118481'} |
| p_value | 0.01 |
| protocol | Retrospective analysis comparing trauma patients receiving blood transfusions who had preinjury ACE-I/ARB exposure versus those without such exposure. Demographics, complications, transfusion volumes, |
| effect_size | 10% versus 17.9% 24-hour mortality (ACE-I/ARB vs control) |
| sample_size | 1013 |
| source_pmid | 41936145 |
| extracted_at | 2026-04-10T15:45:09.115236 |
| _schema_version | 1 |
| experiment_type | clinical |
| success_criteria | Statistically significant difference in mortality rates between ACE-I/ARB exposed and non-exposed groups, with significance maintained after multivariable adjustment |
| expected_outcomes | Based on previous sepsis research showing improved mortality with ACE-I/ARB use, researchers expected potential mortality benefit in trauma patients with preinjury ACE-I/ARB exposure |
| statistical_methods | Univariate analysis, multivariable logistic regression |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
35%
Debates
0
Incoming
7
Outgoing
6
0 supporting
0 contradicting
0 neutral
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