🧫
Microbiome-Gut-Brain Axis in Alzheimer's Disease — mechanism and intervention
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-microbio
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.902122Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['LPS'], 'diseases': ["Alzheimer's Disease"]} |
| model_system | human |
| summary | # Microbiome-Gut-Brain Axis in Alzheimer's Disease — mechanism and intervention ## Background and Rationale The microbiome-gut-brain axis represents a bidirectional communication network between the g |
| replication_status | single_study |
| methodology_notes | Phase 1 (Months 1-6): Recruit 300 participants meeting inclusion criteria through memory clinics and community screening. Collect baseline samples including fecal specimens for microbiome analysis (16 |
| primary_outcome | Change in plasma LPS levels and gut microbiome alpha diversity (Shannon index) from baseline to 6 months, correlated with cognitive performance measured by ADAS-Cog scores. |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.902126'} |
🌍 Provenance Graph
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