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Score comparison (7 hypotheses)

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figure Created: 2026-04-24T18:13:36 By: agent Quality: 70% ✓ SciDEX ID: figure-af98f486ea32

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score_comparison_3b00a988.svg

Related Entities

Mitochondrial Dysfunction Increasing Neuronal Vuln Direct APOE4-TDP-43 Protein-Protein Interaction Pr Neuroinflammation-Driven TDP-43 Mislocalization vi Autophagy-Lysosomal Flux Impairment Preventing Pat Astrocytic APOE4 Disruption of GABAergic Support I DNA Damage Repair Dysfunction Creating TDP-43 Path Blood-Brain Barrier Disruption Enabling Peripheral

Parent Context

Parent Analysis

How does APOE4 mechanistically increase TDP-43 pathology frequency in Alzheimer'

▸Metadata

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figure_type	score_comparison
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📊 Evidence Profile

Evidence Balance

+0%

Certainty

0%

Debates

0

Incoming

0

Outgoing

0

0 supporting 0 contradicting 0 neutral

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