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What determines the threshold between protective and destructive P53 activation?

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open question Created: 2026-04-25T20:29:38 By: backfill_open_questions Quality: 50% ✓ SciDEX ID: open_question-888b57ec-2b00-4aa6-8b1f-c8
Open Question open Wiki: mechanisms-dj1-pten-p53-network
What determines the threshold between protective and destructive P53 activation?
Importance Elo
1500
Field Rank
Rank #1169 in mechanisms
Tractability
0.50
Potential Impact
0.50
Evidence Summary
Extracted from wiki page mechanisms-dj1-pten-p53-network
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statusopen
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-26T03:29:38.183453'}
field_tagmechanisms
source_idmechanisms-dj1-pten-p53-network
sub_fielddj1-pten-p53-network
source_kindwiki
question_hashf0ca11ddb4c720f9675383027b3635f15385532bd55a0613067c4e807415ad78
question_textWhat determines the threshold between protective and destructive P53 activation?
importance_elo1500
_schema_version1
evidence_summaryExtracted from wiki page mechanisms-dj1-pten-p53-network
evidence_xref_at2026-04-27T12:49:38.379075+00:00
tractability_score0.5
potential_impact_score0.5
📊 Evidence Profile
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0%
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Outgoing
1
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