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Do the identified SMN enhancers maintain equivalent cell-type specificity and expression patterns across all mammalian species, including humans?
active
open question
Created: 2026-04-27T23:21:17
By: open_question_miner_papers
Quality:
67%
🔗 External
ID: open_question-genetics-fb58d490
Open Question
open
paper: 40403722
Do the identified SMN enhancers maintain equivalent cell-type specificity and expression patterns across all mammalian species, including humans?
Importance Elo
1500
Field Rank
Rank #3 in genetics
Tractability
0.50
Potential Impact
0.85
Evidence Summary
toolkit will enable future investigations of cell type function across species
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▸Metadata
| status | open |
| _origin | {'url': None, 'type': 'external', 'tracked_at': '2026-04-28T06:21:17.883106'} |
| field_tag | genetics |
| source_id | 40403722 |
| source_doi | 10.1016/j.celrep.2025.115730 |
| source_kind | paper |
| question_hash | fb58d4904ebad764 |
| question_text | Do the identified SMN enhancers maintain equivalent cell-type specificity and expression patterns across all mammalian species, including humans? |
| importance_elo | 1500 |
| _schema_version | 1 |
| source_paper_id | paper-8a4e5bc12333 |
| evidence_summary | toolkit will enable future investigations of cell type function across species |
| tractability_score | 0.5 |
| potential_impact_score | 0.85 |
| is_answerable_in_principle | True |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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