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Effect of Carotenoids from Phaeodactylum tricornutum on Palmitate-Treated HepG2 Cells.
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ID: paper-32575640
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Effect of Carotenoids from Phaeodactylum tricornutum on Palmitate-Treated HepG2 Cells.
Mayer C, Côme M, Blanckaert V, Chini Zittelli G, Faraloni C, Nazih H, Ouguerram K, Mimouni V, Chénais B
Abstract
Non-alcoholic fatty liver disease represents the most common liver disease and is characterized by an excess of lipid accumulation in hepatocytes, mainly stored as triglycerides. Phaeodactylum tricornutum is a marine microalga, which is rich in bioactive molecules known to be hepatoprotective, such as n-3 long-chain polyunsaturated fatty acids and fucoxanthin. The aim of this study was to investigate the effects of a carotenoid extract from P. tricornutum in a cellular model of non-alcoholic fat...
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