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PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
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📄 Paper Details
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C
Abstract
1. Cell. 2023 Feb 16;186(4):786-802.e28. doi: 10.1016/j.cell.2023.01.005. Epub 2023 Feb 7. PIKFYVE inhibition mitigates disease in models of diverse forms of ALS. Hung ST(1), Linares GR(1), Chang WH(2), Eoh Y(1), Krishnan G(3), Mendonca S(2), Hong S(2), Shi Y(1), Santana M(1), Kueth C(4), Macklin-Isquierdo S(4), Perry S(5), Duhaime S(6), Maios C(6), Chang J(1), Perez J(1), Couto A(1), Lai J(1), Li Y(1), Alworth SV(2), Hendricks E(1), Wang Y(7), Zlokovic BV(7), Dickman DK(5), Parker JA(6),...
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📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
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