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Dolutegravir induces endoplasmic reticulum stress at the blood-brain barrier.

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paper Created: 2026-04-03T00:10:32 By: crosslink_script Quality: 15% 🔗 External ID: paper-39985305
📄 Paper Details
Dolutegravir induces endoplasmic reticulum stress at the blood-brain barrier.
Huang C, Qu QR, Hoque MT, Bendayan R
FASEB J PubMed DOI
Abstract

1. FASEB J. 2025 Feb 28;39(4):e70377. doi: 10.1096/fj.202402677RR. Dolutegravir induces endoplasmic reticulum stress at the blood-brain barrier. Huang C(1), Qu QR(1), Hoque MT(1), Bendayan R(1). Author information: (1)Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. Dolutegravir (DTG)-based antiretroviral therapy is the contemporary first-line therapy to treat HIV infection. Despite its efficacy, mounting evidence has ...

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📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting 0 contradicting 0 neutral
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