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Figure 4 — Dopaminergic Epistases in Schizophrenia.
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Created: 2026-04-21T18:29:40
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ID: paper-fig-30ca96c6-1e77-4791-83b7-6ee8af
Figure 4Figure 4
While the functional mechanisms are unclear, a DA gene complex may be associated with certain SZ symptoms, hinting at the idea that DA-associated SZ may represent one out of many different phenotypes. The complex consists of COMT (mainly expressed in the prefrontal cortex), DRD2 (mainly expressed in the striatum, olfactory tubercle, and nucleus accumbens), DAT (substantia nigra, ventral tegmental area, striatum, and nucleus accumbens), and DDC (hypothalamus, striatum, and locus coeruleus) [ 112 ].
▸Metadata
| pmid | 30ca96c6-1e77-4791-83b7-6ee8afff3f62 |
| caption | While the functional mechanisms are unclear, a DA gene complex may be associated with certain SZ symptoms, hinting at the idea that DA-associated SZ may represent one out of many different phenotypes. |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC11592377/bin/brainsci-14-01089-g004.jpg |
| paper_title | Dopaminergic Epistases in Schizophrenia. |
| figure_label | Figure 4 |
| figure_number | 4 |
| _schema_version | 1 |
| source_strategy | pmc_api |
📊 Evidence Profile
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