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Fig. 6: Genetic activation of endothelial Wnt/β-catenin signaling in vivo improves tight...
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Created: 2026-04-16T11:31:41
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Fig. 6Figure 6
Genetic activation of endothelial Wnt/β-catenin signaling in vivo improves tight junctions and reduces transcytosis in mice treated with LPS. A , Representative TEM images from mouse brain cortex tissue showing tight junctions opening induced by LPS and its quantifications presented as percentage of the opening length of the whole tight junction length. n = 3 to 4 mice per group, and each data point represents one tight junction structure. B , Representative TEM images from mouse brain cortex tissue showing endothelial vesicles and its quantifications presented as mean vesicular pit density (vesicles per um endothelial profile). n = 3 to 4 mice per group, and each data point represents one capillary. P, Pericyte; E, endothelial cell; L, lumen; R, red blood cells; TJ, tight junctions. C-E , Co-immunofluorescence staining of tight junction proteins ZO-1 (C) , Claudin-5 (D) , Occludin (E) and CD31 and quantifications in the mouse brain cortex tissue. White arrows indicate blood
▸Metadata
| doi | |
| pmcid | PMC11491032 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC11491032/bin/12974_2024_3261_Fig6_HTML.jpg', 'type': 'external', 'tracked_at': '2026-04-16T11:31:41.969658'} |
| caption | Genetic activation of endothelial Wnt/β-catenin signaling in vivo improves tight junctions and reduces transcytosis in mice treated with LPS. A , Representative TEM images from mouse brain cortex tis |
| paper_id | 39427196 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC11491032/bin/12974_2024_3261_Fig6_HTML.jpg |
| image_path | |
| description | |
| figure_label | Fig. 6 |
| figure_number | 6 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
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