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Fig. 8 — Prolonged anesthesia induces neuroinflammation and complement-mediated microglia
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Created: 2026-04-21T18:29:40
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ID: paper-fig-paper-133bd96a1c04-8
Fig. 8Figure 8
RNA-seq analysis indicated DEGs in the hippocampus enriched in different synaptic pathways, and synapse-related genes were upregulated after microglial depletion. A Volcano map of DEGs. The X -axis represents the fold change of the difference after conversion to log 2 , and the Y -axis represents the significance value after conversion to −log 10 . The red represents 347 DEGs upregulated, the green represents 160 DEGs downregulated, and the gray represents non-DEGs. B KEGG pathway enrichment bubble chart. C GO cellular component enrichment bubble chart. D GO molecular function enrichment bubble chart. E GO biological process enrichment bubble chart. From panels B to E , X -axis is the enrichment ratio (the ratio of the number of genes annotated to an entry in the selected gene set to the total number of genes annotated to the entry in the species), and Y -axis is KEGG pathway or GO term. The size of the bubble represents the number of genes annotated to the KEGG pathwa
▸Metadata
| pmid | paper-133bd96a1c04 |
| caption | RNA-seq analysis indicated DEGs in the hippocampus enriched in different synaptic pathways, and synapse-related genes were upregulated after microglial depletion. A Volcano map of DEGs. The X -axis |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC9814183/bin/12916_2022_2705_Fig8_HTML.jpg |
| paper_title | Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors. |
| figure_label | Fig. 8 |
| figure_number | 8 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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