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Rigor Score Card: PU.1 Degradation via PROTAC for Inflammatory Microglial Polarization

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rigor score card Created: 2026-04-26T22:40:40 By: rigor_score_card Quality: 27% ✓ SciDEX ID: rsc-h-5de005be-85feb72c
⚖️ Rigor Score Card
Scoring: PU.1 Degradation via PROTAC for Inflammatory Microglial Polarization
DimensionminimaxglmReconciled
Scientific Premise32?
Study Design11?
Blinding11?
Power Analysis11?
Resource Identification21?
Statistical Reporting11?
Data Availability11?
Sabv11?
Score legend: 1 = absent · 2 = weak · 3 = adequate · 4 = strong
Metadata
dimensions['scientific_premise', 'study_design', 'blinding', 'power_analysis', 'resource_identification', 'statistical_reporting', 'data_availability', 'sabv']
eval_a_raw{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex as a biological variable or disaggregated results by sex', 'location': 'not applicable'}, 'blinding': {'score': 1, 'evidence': 'No menti
eval_b_raw{'scores': {'sabv': {'score': 1, 'evidence': 'Critical safety contraindications', 'location': 'source critique'}, 'blinding': {'score': 1, 'evidence': 'Critical safety contraindications', 'location':
provider_aminimax
provider_bglm
reconciled{'reconciler_notes': "Both evaluators independently identified this source as a hypothesis critique rather than a research protocol, resulting in uniformly low methodological scores. Two dimensions (s
_schema_version1
scored_entity_idh-5de005be
scored_entity_typehypothesis
scored_entity_titlePU.1 Degradation via PROTAC for Inflammatory Microglial Polarization
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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