Rigor Score Card: TYROBP Causal Network Inhibition for Microglial Repolarization

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rigor score card Created: 2026-04-24T04:44:20 By: rigor_score_card Quality: 30% ✓ SciDEX ID: rsc-h-9e51501a-e06c0fbe

⚖️ Rigor Score Card

Dimension	minimax	glm	Reconciled
Scientific Premise	3	3	?
Study Design	2	2	?
Blinding	1	1	?
Power Analysis	1	1	?
Resource Identification	1	2	?
Statistical Reporting	1	1	?
Data Availability	1	1	?
Sabv	1	1	?

Score legend: 1 = absent · 2 = weak · 3 = adequate · 4 = strong

▸Metadata

dimensions	['scientific_premise', 'study_design', 'blinding', 'power_analysis', 'resource_identification', 'statistical_reporting', 'data_availability', 'sabv']
eval_a_raw	{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex-based analysis in either preclinical studies or proposed clinical trials. Animal experiments (5×FAD mice, APP/PS1 mice) do not specify m
eval_b_raw	{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex as a biological variable or disaggregation by sex', 'location': 'N/A - not addressed'}, 'blinding': {'score': 1, 'evidence': 'No mention
provider_a	minimax
provider_b	glm
reconciled	{'reconciler_notes': "Both evaluators demonstrated high agreement across all 8 rigor dimensions. Only one dimension (resource_identification) showed a score difference of 1 point (A=1, B=2), which was
_schema_version	1
scored_entity_id	h-9e51501a
scored_entity_type	hypothesis
scored_entity_title	TYROBP Causal Network Inhibition for Microglial Repolarization

📊 Evidence Profile

Evidence Balance

+0%

Certainty

0%

Debates

0

Incoming

0

Outgoing

0

0 supporting 0 contradicting 0 neutral

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💬 Discussion