Rigor Score Card: P2RX7-PANX1 Channel Blockade for Neuroinflammatory Cascade Interruption

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rigor score card Created: 2026-04-24T04:40:09 By: rigor_score_card Quality: 35% ✓ SciDEX ID: rsc-h-f886036d-93100675

⚖️ Rigor Score Card

Dimension	minimax	glm	Reconciled
Scientific Premise	3	3	?
Study Design	3	2	?
Blinding	1	1	?
Power Analysis	1	1	?
Resource Identification	2	3	?
Statistical Reporting	1	1	?
Data Availability	1	1	?
Sabv	1	1	?

Score legend: 1 = absent · 2 = weak · 3 = adequate · 4 = strong

▸Metadata

dimensions	['scientific_premise', 'study_design', 'blinding', 'power_analysis', 'resource_identification', 'statistical_reporting', 'data_availability', 'sabv']
eval_a_raw	{'scores': {'sabv': {'score': 1, 'evidence': '[No text mentioning sex differences, male/female subjects, or disaggregated results by sex]', 'location': 'N/A - Sex as biological variable not addressed'
eval_b_raw	{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex as a biological variable, sex-disaggregated analyses, or acknowledgment of potential sex differences in any model system described.', 'l
provider_a	minimax
provider_b	glm
reconciled	{'reconciler_notes': "Both evaluators demonstrated high concordance across all 8 dimensions. All scores differed by ≤1 point, so averaging was applied throughout. Notable: study_design (A=3, B=2 → avg
_schema_version	1
scored_entity_id	h-f886036d
scored_entity_type	hypothesis
scored_entity_title	P2RX7-PANX1 Channel Blockade for Neuroinflammatory Cascade Interruption

📊 Evidence Profile

Evidence Balance

+0%

Certainty

0%

Debates

0

Incoming

0

Outgoing

0

0 supporting 0 contradicting 0 neutral

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💬 Discussion