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Rigor Score Card: Closed-loop tACS targeting EC-II somatostatin interneurons to restore dendritic integration and prev

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rigor score card Created: 2026-04-21T01:07:20 By: rigor_score_card Quality: 40% ✓ SciDEX ID: rsc-h-var-6e963ed4e6-5114b736
⚖️ Rigor Score Card
Scoring: Closed-loop tACS targeting EC-II somatostatin interneurons to restore dendritic integration and prevent tau-mediated HCN channel dysfunction in AD
DimensionminimaxglmReconciled
Scientific Premise44?
Study Design33?
Blinding23?
Power Analysis11?
Resource Identification22?
Statistical Reporting11?
Data Availability11?
Sabv11?
Score legend: 1 = absent · 2 = weak · 3 = adequate · 4 = strong
Metadata
dimensions['scientific_premise', 'study_design', 'blinding', 'power_analysis', 'resource_identification', 'statistical_reporting', 'data_availability', 'sabv']
eval_a_raw{'scores': {'sabv': {'score': 1, 'evidence': 'Transgenic AD mouse models show selective SST interneuron vulnerability', 'location': 'Preclinical Evidence'}, 'blinding': {'score': 2, 'evidence': 'then
eval_b_raw{'scores': {'sabv': {'score': 1, 'evidence': 'Transgenic AD mouse models show selective SST interneuron vulnerability with co-localization of tau aggregates and reduced HCN1 immunoreactivity in entorh
provider_aminimax
provider_bglm
reconciled{'reconciler_notes': 'Evaluators A and B showed high agreement. Seven of eight dimensions had identical scores, and the only score difference was blinding, where A scored 2 and B scored 3. Because the
_schema_version1
scored_entity_idh-var-6e963ed4e6
scored_entity_typehypothesis
scored_entity_titleClosed-loop tACS targeting EC-II somatostatin interneurons to restore dendritic integration and prevent tau-mediated HCN channel dysfunction in AD
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
1
0 supporting 0 contradicting 0 neutral
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