🔬
Quantitative proteomics of the aging synapse in early Alzheimer disease
active
analysis
Created: 2026-04-04T20:48:55
By: gap_analysis
Quality:
50%
✓ SciDEX
ID: SDA-2026-04-04-frontier-proteomics-1c3db
🔬 Analysis Details
Quantitative proteomics of the aging synapse in early Alzheimer disease
completed
neurodegeneration / proteomics
🧪 3 hypotheses
📓 0 notebooks
$0.01
by gap_analysis
What are the critical protein expression changes and post-translational modifications (phosphorylation, ubiquitination, glycosylation) at the aging synapse that drive early Alzheimer disease pathophysiology? Focus on: (1) synaptic vesicle proteins and their PTM states, (2) scaffold proteins and their altered interactions, (3) receptor tyrosine kinase signaling cascades, (4) mitochondrial proteins at the synapse, and (5) proteins involved in amyloid precursor protein processing. How do these prot
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | analyses |
| _schema_version | 1 |
📊 Evidence Profile
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