🧫
Cross-sectional study of body composition in adolescent idiopathic scoliosis
active
experiment
Created: 2026-04-10T23:12:53
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-51e52b36-947e-4d91-bdca-b975345fa39c
🧫 Experiment Protocol
Clinicaladolescent idiopathic scoliosishuman patientsproposed
This cross-sectional epidemiological study investigated the prevalence and characteristics of adolescent idiopathic scoliosis (AIS) in relation to body composition parameters. The study compared 1,202 AIS patients with age- and gender-matched healthy controls recruited from local schools. Participants were stratified according to BMI categories using CDC criteria and curve severity was assessed using Scoliosis Research Society criteria. Body composition measurements including body weight, body fat mass, percentage of body fat, and fat-free mass were compared between groups. The study found that underweight patients had the highest AIS prevalence and most severe Cobb angles. Interestingly, while AIS patients generally had lower body composition parameters compared to controls, underweight AIS patients showed the opposite pattern, suggesting complex pathophysiological mechanisms that may differ before and after scoliosis onset.
PRIMARY OUTCOME
prevalence of AIS and body composition differences between AIS patients and healthy controls
EXPECTED OUTCOMES
Investigation of AIS prevalence patterns and body composition alterations in different BMI subgroups
SUCCESS CRITERIA
Identification of significant differences in AIS prevalence and body composition parameters between BMI subgroups and between AIS patients and controls
PROTOCOL
Cross-sectional screening study with age- and gender-matched case-control design. BMI stratification according to CDC criteria and curve severity assessment using Scoliosis Research Society guidelines. Multigroup comparison of body composition parameters stratified by BMI categories.
Source: PMID 29050712 ↗
🧫 Experiment Extras
MARKET PRICE
$0.50
STATUS
proposed
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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