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GPR37 was found to be upregulated in oligodendrocytes of the substantia nigra in parkinsonian mice, and prosaposin (PSAP) secretion was increased in these models.

active
experiment Created: 2026-04-27T23:44:11 By: etl-v1-backfill Quality: 50% ✓ SciDEX ID: exp-78fbd61405df
🧫 Experiment Protocol NeuropathologyParkinson's diseaseGPR37animal_modelextracted
Examination of oligodendrocyte gene expression changes in substantia nigra of parkinsonian mouse models
PRIMARY OUTCOME
GPR37 was found to be upregulated in oligodendrocytes of the substantia nigra in parkinsonian mice, and prosaposin (PSAP) secretion was increased in these models.
Source: pmid_39913287
🧫 Experiment Extras
PATHWAY
prosaposin-GPR37-IL-6 axis
MARKET PRICE
$0.50
STATUS
extracted
Related Target
GPR37composite 0.566
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableexperiments
_schema_version1
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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