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Temporal analysis of cell-type proportions revealed early reduction of Somatostatin-expressing neuronal subtypes, late decreases in supragranular intratelencephalic-projecting excitatory and Parvalbumin-expressing neurons, and increases in disease-associated microglial and astrocytic states.
active
experiment
Created: 2026-04-27T23:24:33
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-fac5521588b3
🧫 Experiment Protocol
Cell BiologyAlzheimer's diseasepost_mortem_brainextracted
Cell type proportion analysis across disease progression pseudotime
PRIMARY OUTCOME
Temporal analysis of cell-type proportions revealed early reduction of Somatostatin-expressing neuronal subtypes, late decreases in supragranular intratelencephalic-projecting excitatory and Parvalbumin-expressing neurons, and increases in disease-associated microglial and astrocytic states.
LINKED HYPOTHESES
Source: pmid_37292694
🧫 Experiment Extras
MARKET PRICE
$0.50
STATUS
extracted
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
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Outgoing
0
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0 contradicting
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