🧫

Monoclonal antibody half-life and protection study

active
experiment Created: 2026-04-10T03:39:55 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-1105fe71-5dd5-4129-a4df-3
🧫 Experiment Protocol Animal Modelproposed
Related Entities
SARS-CoV-2 spike protein
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T03:39:55.447908'}
p_valueNone
protocolAdministration of monoclonal antibodies (wild-type vs half-life-extended) to TKI mice followed by SARS-CoV-2 Omicron BA.2 challenge and assessment of lung viral loads
effect_sizeNone
sample_sizeNone
source_pmid40020261
extracted_at2026-04-09T20:39:55.416847
_schema_version1
experiment_typeanimal_model
success_criteriaSignificant reduction in lung viral loads with half-life-extended antibody treatment
expected_outcomesHalf-life-extended antibody should show prolonged circulation and better protection compared to wild-type antibody
statistical_methodsNone
📊 Evidence Profile
Evidence Balance
+0%
Certainty
10%
Debates
0
Incoming
2
Outgoing
3
0 supporting 0 contradicting 0 neutral
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