🧫
REV-ERB pharmacological activation blocks SD effects
active
experiment
Created: 2026-04-11T00:49:32
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-8044c862-0843-458a-b6c7-8
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:49:32.275568'} |
| p_value | None |
| protocol | REV-ERB agonist administration followed by sleep deprivation and behavioral assessment |
| effect_size | None |
| sample_size | None |
| source_pmid | 41023421 |
| extracted_at | 2026-04-10T17:49:32.189587 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Significant reduction in antidepressant behavioral response compared to vehicle-treated controls |
| expected_outcomes | Suppression of sleep deprivation's antidepressant effects by REV-ERB activation |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
55%
Debates
0
Incoming
11
Outgoing
9
0 supporting
0 contradicting
0 neutral
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