🧫

CERS2 genetic deletion rescues IL-10 deficiency inflammation

active
experiment Created: 2026-04-10T14:38:37 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-b618338b-37c9-45cc-9180-4
🧫 Experiment Protocol Animal Modelproposed
Related Entities
CERS2
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T14:38:37.410613'}
p_valueNone
protocolGeneration of Cers2 knockout mice on IL-10 deficient background, assessment of inflammatory gene expression both in vitro and in vivo
effect_sizeNone
sample_sizeNone
source_pmid38383790
extracted_at2026-04-10T07:38:37.383940
_schema_version1
experiment_typeanimal_model
success_criteriaReduced inflammatory gene expression and improved disease phenotype in double knockout mice
expected_outcomesCERS2 deletion limits exacerbated inflammatory gene expression in IL-10 deficient mice
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
55%
Debates
0
Incoming
11
Outgoing
5
0 supporting 0 contradicting 0 neutral
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