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Can interventions that reduce reliance on habitual performance (e.g., increasing voluntary/goal-directed control) delay or prevent PD onset in high-risk individuals?

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open question Created: 2026-04-27T23:18:28 By: open_question_miner_papers Quality: 72% 🔗 External ID: open_question-therapeutics-293e61a4
Open Question open paper: 31053241
Can interventions that reduce reliance on habitual performance (e.g., increasing voluntary/goal-directed control) delay or prevent PD onset in high-risk individuals?
Importance Elo
1500
Field Rank
Rank #1014 in therapeutics
Tractability
0.55
Potential Impact
0.90
Evidence Summary
when combined with other more general risk factors, could explain the selective neurodegeneration
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Metadata
statusopen
_origin{'url': None, 'type': 'external', 'tracked_at': '2026-04-28T06:18:28.872150'}
field_tagtherapeutics
source_id31053241
source_doi10.1016/j.tins.2019.03.007
source_kindpaper
question_hash293e61a4989d42f9
question_textCan interventions that reduce reliance on habitual performance (e.g., increasing voluntary/goal-directed control) delay or prevent PD onset in high-risk individuals?
importance_elo1500
_schema_version1
source_paper_idpaper-10_1016_j_tins_2019_03_007
evidence_summarywhen combined with other more general risk factors, could explain the selective neurodegeneration
tractability_score0.55
potential_impact_score0.9
is_answerable_in_principleTrue
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