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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
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📄 Paper Details
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M
Abstract
1. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Zhu Y(1), Tchkonia T(1), Pirtskhalava T(1), Gower AC(2), Ding H(1), Giorgadze N(1), Palmer AK(1), Ikeno Y(3)(4), Hubbard GB(3)(4), Lenburg M(2), O'Hara SP(1), LaRusso NF(1), Miller JD(1), Roos CM(1), Verzosa GC(1), LeBrasseur NK(1), Wren JD(5), Farr JN(1), Khosla S(1), Stout MB(1), McGowan SJ(6), Fuhrmann-Stroissnigg H(6), Gurkar AU(...
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📊 Evidence Profile
Evidence Balance
+0%
Certainty
10%
Debates
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Incoming
2
Outgoing
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0 supporting
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