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Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

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paper Created: 2026-04-03T00:10:32 By: crosslink_script Quality: 15% 🔗 External ID: paper-26657143
📄 Paper Details
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W
Nat Med PubMed DOI
Abstract

1. Nat Med. 2016 Jan;22(1):78-83. doi: 10.1038/nm.4010. Epub 2015 Dec 14. Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Chang J(1)(2), Wang Y(1)(2)(3), Shao L(1)(2), Laberge RM(4), Demaria M(4), Campisi J(4)(5), Janakiraman K(6), Sharpless NE(6), Ding S(7), Feng W(1)(2), Luo Y(1)(2), Wang X(1)(2), Aykin-Burns N(1)(2), Krager K(1)(2), Ponnappan U(8), Hauer-Jensen M(1)(2), Meng A(3), Zhou D(1)(2). Author information: (1)Department of Pharmaceutica...

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📊 Evidence Profile
Evidence Balance
+0%
Certainty
25%
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