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Erchen decoction and its active flavonoids hesperidin and quercetin alleviate high-fat diet-induced neuroinflammation by targeting HK2-mediated microglial glycolysis.
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ID: paper-41921767
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Erchen decoction and its active flavonoids hesperidin and quercetin alleviate high-fat diet-induced neuroinflammation by targeting HK2-mediated microglial glycolysis.
Zheng M, Yang K, Ma Y, Suo W, Li J, Huang Y, Gao P, Liu K, Zhang Y, Liu H, Guan L, Yan F, Xu J, Liu T, Xu J
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Erchen decoction (ECD), a classic Traditional Chinese Medicine formula recorded in the Taiping Huimin Heji Ju Fang, is historically recognized as the fundamental prescription for drying dampness and resolving phlegm. While ECD is widely used in modern clinical practice for metabolic disorders, the pharmacological mechanisms linking its traditional indications to the regulation of obesity-associated neuroinflammation remain elusive. AIM OF THE STUDY: This study aim...
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