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Figure 4.: Epigenetic dysregulations in synucleinopathy patients’ appendices. (A) The volc...
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Figure 4.Figure 4
Epigenetic dysregulations in synucleinopathy patients’ appendices. (A) The volcano plot displays differential methylation between synucleinopathy appendices (n=11) and controls, (n=13) with the x-axis showing beta value differences (synucleinopathy – control). Blue dots represent observations that were significantly different in both p-value and beta value. (B) The total number of hypomethylated and hypermethylated CpG sites exhibiting more hypomethylation in synucleinopathy appendix as compared to controls. (C) The distribution of number of CpG sites across various gene regions in synucleinopathy appendices compared to controls. (D) The distribution of number of CpG sites across CpG regions in synucleinopathy appendices compared to controls.
▸Metadata
| doi | |
| pmcid | PMC12632551 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC12632551/bin/nihpp-2025.10.07.680938v1-f0004.jpg', 'type': 'external', 'tracked_at': '2026-04-28T07:22:23.643500'} |
| caption | Epigenetic dysregulations in synucleinopathy patients’ appendices. (A) The volcano plot displays differential methylation between synucleinopathy appendices (n=11) and controls, (n=13) with the x-axi |
| paper_id | 41279937 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC12632551/bin/nihpp-2025.10.07.680938v1-f0004.jpg |
| image_path | |
| description | |
| figure_label | Figure 4. |
| figure_number | 4 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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