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Fig. 1. — Prolonged anesthesia induces neuroinflammation and complement-mediated microglia
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Created: 2026-04-21T18:29:40
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Fig. 1.Figure 1
Prolonged anesthesia caused cognitive dysfunction and anxiety-like behaviors in rats. A The schedule of the first experiment. Rats underwent 5 days of swimming training in the MWM. Then, 3% sevoflurane was exposed to rats for 4 h to induce SIN rats. Probe trials were performed on the first and third days after sevoflurane exposure. On the first day after sevoflurane exposure, we harvested brain tissues. B, C Prolonged anesthesia by sevoflurane caused cognitive dysfunction in rats. It reduced the time and number of entering the platform quadrant of rats. D, E The before-after with SD chart of the MWM test in the control group. F, G The before-after with SD chart of the MWM test in Sevo group. H, I In OFT, prolonged anesthesia caused anxiety-like behaviors in rats. It decreased the time and number of entering the central region of rats. J, K In EPM, prolonged anesthesia caused anxiety-like behaviors in rats. It decreased the number and time of entering opened arms of rats. D
▸Metadata
| pmid | paper-133bd96a1c04 |
| caption | Prolonged anesthesia caused cognitive dysfunction and anxiety-like behaviors in rats. A The schedule of the first experiment. Rats underwent 5 days of swimming training in the MWM. Then, 3% sevoflur |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC9814183/bin/12916_2022_2705_Fig1_HTML.jpg |
| paper_title | Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors. |
| figure_label | Fig. 1. |
| figure_number | 1 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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