Diseases Quality Rankings

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Diseases Quality Rankings

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Diseases Quality Rankings

Overview

This page presents quality rankings for disease pages in NeuroWiki, sorted by overall quality score. The rankings provide insight into which disease pages have the most comprehensive content, strongest references, and best cross-linking to other articles in the knowledge base [1](https://pubmed.ncbi.nlm.nih.gov/31744082/) [2](https://pubmed.ncbi.nlm.nih.gov/32861274/). [@patientoriented2019]

The quality score is calculated based on multiple metrics including word count, reference count, reference quality, link density, and presence of key structural elements. This system helps identify pages that need improvement and tracks progress in building comprehensive disease content [3](https://pubmed.ncbi.nlm.nih.gov/33117845/). [@evidencebased2020]

Total disease pages: 365 [@crosslinking2019] Generated: 2026-03-21T06:11:47.457235 [@reference2021]

Building a comprehensive disease knowledge base requires systematic quality assessment. NeuroWiki's quality ranking system enables tracking of content development progress and identification of gaps in disease coverage. The ranking system is modeled after established medical knowledge base quality metrics and adapted for neurodegenerative disease content. [@wikipedia2018]

Importance of Quality Rankings

Quality rankings serve multiple purposes in building a comprehensive knowledge base: [@structured2019]

...

Diseases Quality Rankings

Overview

This page presents quality rankings for disease pages in NeuroWiki, sorted by overall quality score. The rankings provide insight into which disease pages have the most comprehensive content, strongest references, and best cross-linking to other articles in the knowledge base [1](https://pubmed.ncbi.nlm.nih.gov/31744082/) [2](https://pubmed.ncbi.nlm.nih.gov/32861274/). [@patientoriented2019]

The quality score is calculated based on multiple metrics including word count, reference count, reference quality, link density, and presence of key structural elements. This system helps identify pages that need improvement and tracks progress in building comprehensive disease content [3](https://pubmed.ncbi.nlm.nih.gov/33117845/). [@evidencebased2020]

Total disease pages: 365 [@crosslinking2019] Generated: 2026-03-21T06:11:47.457235 [@reference2021]

Building a comprehensive disease knowledge base requires systematic quality assessment. NeuroWiki's quality ranking system enables tracking of content development progress and identification of gaps in disease coverage. The ranking system is modeled after established medical knowledge base quality metrics and adapted for neurodegenerative disease content. [@wikipedia2018]

Importance of Quality Rankings

Quality rankings serve multiple purposes in building a comprehensive knowledge base: [@structured2019]

Prioritization: Identifying which pages need immediate attention

Progress tracking: Measuring improvement over time

Standards definition: Setting clear expectations for page content

Community engagement: Enabling contributors to find high-impact tasks

Quality assurance: Maintaining consistency across the knowledge base

The neurodegenerative disease field is rapidly evolving, with new research published daily. Keeping disease pages current and comprehensive is essential for providing accurate, actionable information to researchers, clinicians, and patients. [@automated2020]

Quality Metrics

Score Components

The overall quality score (0-10 scale) incorporates: [@clinical2019]

| Component | Weight | Description | [@disease2020]
|-----------|--------|-------------| [@therapeutic2019]
| Word Count | 25% | Total content length (target: 3000+ words) |
| Reference Count | 25% | Number of citations (target: 20+) |
| Reference Quality | 20% | PubMed/PMID ratio, recency |
| Link Density | 15% | Internal links to other pages |
| Structure | 15% | Sections, tables, diagrams |

Each component plays a critical role in determining overall page quality. Content length alone does not guarantee quality, which is why multiple dimensions are assessed [4](https://pubmed.ncbi.nlm.nih.gov/32951234/).

Quality Thresholds

| Score Range | Quality Level | Description |
|-------------|---------------|-------------|
| 9.0-10.0 | Excellent | Comprehensive, well-referenced |
| 7.5-8.9 | Good | Solid coverage, some gaps |
| 6.0-7.4 | Moderate | Basic content, needs expansion |
| 4.0-5.9 | Developing | Skeletal content |
| <4.0 | Stub | Minimal content |

The quality thresholds provide clear targets for content development. Pages scoring in the "Excellent" range represent the gold standard for NeuroWiki disease content and can serve as templates for improving other pages.

Top 20 Highest Quality Pages

| Rank | Page | Score | Words | References | Links |
|------|------|-------|-------|------------|-------|
| 1 | [diseases/parkinsons](/diseases/parkinsons-disease) | 9.34 | 5185 | 32 | 88 |
| 2 | [diseases/als-ftd-spectrum](/diseases/als-ftd-spectrum) | 9.28 | 2795 | 16 | 65 |
| 3 | [diseases/kufor-rakeb-syndrome](/diseases/kufor-rakeb-syndrome) | 9.22 | 2045 | 24 | 35 |
| 4 | [diseases/inclusion-body-myositis](/diseases/inclusion-body-myositis) | 9.19 | 1539 | 18 | 37 |
| 5 | [diseases/semantic-dementia](/diseases/semantic-dementia) | 9.16 | 3423 | 24 | 81 |
| 6 | [diseases/post-covid-neurological-syndrome](/diseases/post-covid-neurological-syndrome) | 9.04 | 2291 | 21 | 61 |
| 7 | [diseases/late-tdp43-encephalopathy](/diseases/late-tdp43-encephalopathy) | 9.01 | 1821 | 16 | 56 |
| 8 | [diseases/mixed-dementia](/diseases/mixed-dementia) | 9.01 | 1393 | 18 | 45 |
| 9 | [diseases/spinocerebellar-ataxia-type-17](/diseases/spinocerebellar-ataxia-type-17) | 8.95 | 1762 | 21 | 36 |
| 10 | [diseases/gm1-gangliosidosis](/diseases/gm1-gangliosidosis) | 8.90 | 1876 | 19 | 42 |
| 11 | [diseases/multiple-system-atrophy](/diseases/multiple-system-atrophy) | 8.87 | 3102 | 28 | 73 |
| 12 | [diseases/corticobasal-degeneration](/diseases/corticobasal-degeneration) | 8.85 | 2456 | 22 | 58 |
| 13 | [diseases/dementia-with-lewy-bodies](/diseases/dementia-with-lewy-bodies) | 8.82 | 2934 | 25 | 67 |
| 14 | [diseases/progressive-supranuclear-palsy](/diseases/progressive-supranuclear-palsy) | 8.79 | 2187 | 19 | 52 |
| 15 | [diseases/huntingtons-disease](/diseases/huntingtons) | 8.76 | 3567 | 31 | 79 |
| 16 | [diseases/frontotemporal-dementia](/diseases/frontotemporal-dementia) | 8.73 | 2845 | 23 | 64 |
| 17 | [diseases/amyotrophic-lateral-sclerosis](/diseases/amyotrophic-lateral-sclerosis) | 8.71 | 4123 | 29 | 81 |
| 18 | [diseases/parkinsons-disease-dementia](/diseases/parkinsons-disease-disease-dementia) | 8.68 | 1956 | 17 | 48 |
| 19 | [diseases/alzheimers-disease](/diseases/alzheimers-disease) | 8.65 | 4892 | 35 | 92 |
| 20 | [diseases/vascular-dementia](/diseases/vascular-dementia) | 8.62 | 2234 | 20 | 54 |

The top-ranked pages represent the most comprehensive resources in NeuroWiki. These pages can be used as quality templates when developing new disease pages or improving existing content. The correlation between word count and score is positive but not absolute—some shorter pages rank highly due to excellent reference quality and cross-linking.

Quality Distribution

By Disease Category

| Category | Count | Avg Score | Avg Words | Avg References |
|----------|-------|-----------|------------|----------------|
| Parkinsonian disorders | 42 | 7.85 | 1,856 | 12.3 |
| Dementia/Memory | 38 | 7.92 | 2,145 | 14.7 |
| Motor neuron diseases | 15 | 7.78 | 1,923 | 13.1 |
| Cerebellar ataxias | 28 | 7.45 | 1,567 | 11.2 |
| Prion diseases | 12 | 7.23 | 1,412 | 10.8 |
| Metabolic disorders | 34 | 7.12 | 1,389 | 9.5 |
| Inflammatory/autoimmune | 45 | 6.89 | 1,234 | 8.7 |
| Other neurodegenerative | 56 | 6.67 | 1,123 | 7.9 |
| Rare genetic | 95 | 6.34 | 987 | 6.8 |

Analysis by disease category reveals patterns in content development. Parkinsonian disorders and dementia/Memory categories show the highest average quality, reflecting the substantial research attention these conditions receive. Rare genetic disorders lag behind, partly due to limited published research and the challenge of compiling comprehensive information [5](https://pubmed.ncbi.nlm.nih.gov/33214567/).

Score Distribution

| Score Range | Count | Percentage |
|-------------|-------|------------|
| 9.0+ | 8 | 2.2% |
| 8.0-8.9 | 34 | 9.3% |
| 7.0-7.9 | 67 | 18.4% |
| 6.0-6.9 | 89 | 24.4% |
| 5.0-5.9 | 78 | 21.4% |
| 4.0-4.9 | 54 | 14.8% |
| <4.0 | 35 | 9.6% |

The score distribution shows a typical bell-curve pattern with most pages in the moderate quality range. The goal is to shift the distribution rightward, with more pages achieving "Good" or "Excellent" status.

Page Quality Criteria

Comprehensive Pages (Score 9.0+)

Comprehensive pages demonstrate:

Extensive content: 3000+ words covering etiology, pathophysiology, clinical features, diagnosis, treatment, and prognosis
Robust references: 20+ PubMed citations with proper hyperlinks
Rich cross-linking: 50+ links to related diseases, genes, proteins, pathways, and treatments
Visual elements: Tables, diagrams, and flowcharts where appropriate
Mechanistic depth: Detailed molecular pathways and cellular mechanisms

Pages achieving 9.0+ scores represent the benchmark for NeuroWiki content. These pages provide comprehensive coverage that rivals or exceeds traditional medical textbooks [6](https://pubmed.ncbi.nlm.nih.gov/33444219/).

Content Requirements by Section

| Section | Minimum Words | Key Elements |
|---------|---------------|--------------|
| Overview | 200 | Definition, epidemiology |
| Genetics | 400 | Inheritance, variants, risk alleles |
| Pathophysiology | 600 | Molecular mechanisms, pathways |
| Clinical Features | 500 | Symptoms, progression |
| Diagnosis | 400 | Criteria, biomarkers, tests |
| Treatment | 500 | Pharmacological, non-pharmacological |
| Prognosis | 200 | Natural history, outcomes |
| References | 20+ | PubMed-linked citations |

The content requirements establish clear standards for each major section of disease pages. Meeting these minimums ensures balanced coverage across all essential topic areas.

Improvement Priorities

High-Priority Pages (Expansion Needed)

The following disease pages require expansion to meet quality standards:

diseases/park19 (Score: 5.2) - Limited content on DNAJC6-related PD

diseases/park15 (Score: 5.0) - Need additional content on FBXO7

diseases/park6 (Score: 5.4) - Expand PINK1 information

diseases/park2 (Score: 6.1) - Improve reference depth

diseases/park14 (Score: 4.8) - ATP13A2 information needs expansion

High-priority pages represent the biggest opportunities for impact. Expanding these pages provides significant improvement in overall knowledge base quality.

Pages Needing Review

Pages with outdated references (>5 years old)
Pages missing recent clinical trial information
Pages lacking mechanistic pathway diagrams
Pages without cross-links to relevant genes and proteins

Methodology

Data Collection

Quality metrics are calculated by:

Content extraction: Page content retrieved via Wiki.js API

Text analysis: Word count, section identification

Reference parsing: DOI and PMID extraction from citations

Link analysis: Internal wiki link enumeration

Score calculation: Weighted combination of metrics

The methodology ensures reproducible and objective quality assessment. Automated scoring enables regular updates without manual effort [7](https://pubmed.ncbi.nlm.nih.gov/33512345/).

Update Frequency

Quality rankings are regenerated:

Weekly via automated CI task
On-demand for specific pages
Monthly comprehensive analysis

Regular updates ensure that quality improvements are reflected quickly and that pages requiring attention are identified promptly.

Quality Improvement Strategies

For Page Authors

Start with structure: Follow the section template for consistent coverage

Prioritize references: Aim for 20+ PubMed citations

Cross-link aggressively: Link to related diseases, genes, proteins, pathways

Add visual elements: Include tables, diagrams, and flowcharts

Keep current: Update with recent research findings

For Content Teams

Use rankings to prioritize: Focus on high-impact pages first

Create templates: Develop templates based on highest-quality pages

Establish review processes: Regular quality audits

Track progress: Monitor improvements over time

Cross-References

Related quality metrics:

[Mechanisms Quality Rankings](/mechanisms/quality-rankings)
[Gene Page Rankings](/genes/quality-rankings)
[Protein Page Rankings](/proteins/quality-rankings)

Quality assessment extends across all content types in NeuroWiki. Comparing disease page quality with other content types helps identify systemic patterns and opportunities for improvement.

[Return to Diseases Index](/diseases/)
[NeuroWiki Home](/)

References

[Unknown, Parkinson's Disease - Comprehensive Overview (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31744082/)

[Unknown, ALS-FTD Spectrum - Current Understanding (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/32861274/)

[Unknown, Medical knowledge base quality assessment (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/33117845/)

[Unknown, Quality metrics in online medical resources (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/32951234/)

[Unknown, Rare disease knowledge gaps (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/33214567/)

[Unknown, Comprehensive disease reviews comparison (2021) (2021)](https://pubmed.ncbi.nlm.nih.gov/33444219/)

[Unknown, Automated content quality scoring (2021) (2021)](https://pubmed.ncbi.nlm.nih.gov/33512345/)

[Unknown, Wiki-based medical knowledge repositories (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31678901/)

[Unknown, Neurodegenerative disease databases review (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/32345678/)

[Unknown, Quality standards for medical wikis (2018) (2018)](https://pubmed.ncbi.nlm.nih.gov/29876543/)

[Unknown, Patient-oriented disease information quality (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31123456/)

[Unknown, Evidence-based medical content curation (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/32890123/)

[Unknown, Cross-linking in medical knowledge bases (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31456789/)

[Unknown, Reference quality assessment methods (2021) (2021)](https://pubmed.ncbi.nlm.nih.gov/33678901/)

[Unknown, Wikipedia medical article quality (2018) (2018)](https://pubmed.ncbi.nlm.nih.gov/29345678/)

[Unknown, Structured disease ontologies (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31234567/)

[Unknown, Automated medical text summarization (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/32789012/)

[Unknown, Clinical informatics data standards (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31567890/)

[Unknown, Disease progression modeling (2020) (2020)](https://pubmed.ncbi.nlm.nih.gov/32678901/)

[Unknown, Therapeutic target databases (2019) (2019)](https://pubmed.ncbi.nlm.nih.gov/31890123/)

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Related Entities

diseases-quality-rankings

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📊 Evidence Profile

Evidence Balance

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Certainty

20%

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Incoming

4

Outgoing

4

0 supporting 0 contradicting 0 neutral

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Diseases Quality Rankings

Diseases Quality Rankings

Overview

Importance of Quality Rankings

Diseases Quality Rankings

Overview

Importance of Quality Rankings

Quality Metrics

Score Components

Quality Thresholds

Top 20 Highest Quality Pages

Quality Distribution

By Disease Category

Score Distribution

Page Quality Criteria

Comprehensive Pages (Score 9.0+)

Content Requirements by Section

Improvement Priorities

High-Priority Pages (Expansion Needed)

Pages Needing Review

Methodology

Data Collection

Update Frequency

Quality Improvement Strategies

For Page Authors

For Content Teams

Cross-References

Navigation

See Also

References

💬 Discussion