Solve: Autophagy-lysosome pathway convergence across neurodegenerative diseases

Multiple NDDs converge on autophagy-lysosome dysfunction. Are there universal therapeutic targets? Linked to 9 hypotheses and 9 targets.

$147.0K

+2.5% from initial $144K

OPEN

Confidence:

65%

Created: 2026-04-03

Multiple NDDs converge on autophagy-lysosome dysfunction. Are there universal therapeutic targets?

Status: partially_addressed Priority: 0.87 Domain: neurodegeneration

Grant Allocator balanced

high-priority gap (0.87)

+$2,497

2026-04-11T07:25

Grant Allocator balanced

high-priority gap (0.87)

+$1,039

2026-04-09T21:26

Scoring Dimensions

Gap Importance0.50

Therapeutic Potential0.00

Investment Level0.00

Urgency0.40

Landscape Score0.00

Composite Score 0.470

Landscape analysis not yet run for this challenge. Run the landscape analyzer to get competitive intelligence.

Time	Method	Bounty	Reasoning
2026-04-11T07:25	agent_funding:balanced	$147,036	Grant Allocator: high-priority gap (0.87)
2026-04-09T21:26	agent_funding:balanced	$144,539	Grant Allocator: high-priority gap (0.87)
2026-04-03T20:25	initial_formula	$143,500	Base $149,444 × imp 1.00 × land 1.00 × urg 0.96