gene

aifm2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about aifm2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	AIFM2
Full Name	Apoptosis-Inducing Factor Mitochondria-Like 2
Chromosome	10q22.2
Protein Type	Gene
Function	is a mitochondrial flavoprotein homologous to AIFM1 (Apoptosis-Inducing Factor Mitochondria 1).
Molecular Weight	53 kDa
Amino Acids	480 aa
GeneCards	AIFM2
Human Protein Atlas	AIFM2
FAD-binding domain	Essential for oxidoreductase activity
NADH-binding site	Enables electron transfer reactions
C-terminal domain	Involved in protein-protein interactions
Mitochondrial respiration	Contributes to electron transport chain function
Redox balance	Helps maintain cellular NAD+/NADH ratios
Metabolic regulation	Links energy metabolism to cell survival decisions
Associated Diseases	Neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

AIFM2 — Apoptosis-Inducing Factor Mitochondria-Like 2

gene · 1242 words

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Pathway Diagram

graph TD
    A["Regulatory elements"] --> B["aifm2 gene"]
    B --> C["mRNA transcript"]
    C --> D["Protein product"]
    D --> E["Cellular function"]
    E --> F["Disease relevance"]
    B --> G["Variant effects"]
    G --> F
    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    class B gene
    class D protein

Outgoing (1)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:AIFM2	data_in	dataset_row	0.00

Incoming (1)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:AIFM2	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning aifm2 in their description or question text

No additional research found