Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ALS progression: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Prion-Like Propagation | associated_with | mechanism | 0.85 |
| Prion-Like Properties | mediates | mechanism | 0.80 |
| Clinical Predictors | biomarker_for | biomarker | 0.80 |
| AUTOPHAGY | modulates | process | 0.75 |
| microglial xCT deletion | slows | process | 0.70 |
| Microglial xCT | causes | protein | 0.70 |
| sex hormones | associated_with | compound | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 12 hypotheses Top: 0.847
neurodegeneration | 2026-04-16 | 7 hypotheses Top: 0.680
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.33 · 2026-04-27
closed · Rounds: 4 · Score: 0.50 · 2026-04-26
closed · Rounds: 6 · Score: 0.75 · 2026-04-26
closed · Rounds: 5 · Score: 0.59 · 2026-04-16
Hypotheses and analyses mentioning ALS progression in their description or question text
No additional research found