APLP1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolAPLP1
Nameamyloid beta precursor like protein 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding diff

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This is an externally resolved entity

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