protein

BICD2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BICD2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

BICD2 (Bicaudal D2) is a critical cytoplasmic dynein-dynactin adaptor protein that serves as a molecular bridge between dynein motor proteins and their diverse cargoes.

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🔬 Protein Info

Gene Symbol	BICD2PROTEIN
Chromosome	9q34.3
Protein Type	Adaptor Protein
Function	is a critical cytoplasmic dynein-dynactin adaptor protein that serves as a molecular bridge between dynein motor proteins and their diverse cargoes.
Amino Acids	835 aa
Exons	26
GeneCards	BICD2PROTEIN
Human Protein Atlas	BICD2PROTEIN
TATA box	Positioned at -30 relative to transcription start
Neural-specific elements	Binding sites for Ngn2 and NeuroD1
Activity-dependent CRE	Response element for neuronal activity
Growth factor-responsive regions	STAT and NF-κB binding sites
Associated Diseases	Als, Cancer
KG Connections	12 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

bicd2-protein

protein · 1916 words

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Pathway Diagram

graph TD
    BICD2PROTEIN["BICD2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    BICD2PROTEIN -->|"implicated_in"| neurodegeneration
    style BICD2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning BICD2PROTEIN in their description or question text

No additional research found