Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BORC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | BORC |
| Key Genes/Proteins | Mitochondrial Proteins, RNA, AXON, AND, NEURODEGENERATIVE DISORDERS |
| Related Diseases | Axonal Mrna Depletion |
| Related Pathways | Oxidative Phosphorylation |
graph TD
BORC["BORC"]
BORC -->|"regulates"| Lysosome_Related_Vesicle_Trans["Lysosome-Related Vesicle Transport"]
BORC -->|"mediates"| Axonal_mRNA_Transport["Axonal mRNA Transport"]
BORC -->|"regulates"| Mitochondrial_Proteins["Mitochondrial Proteins"]
BORC -->|"regulates"| axonal_mRNA_transport["axonal mRNA transport"]
BORC -->|"interacts"| lysosome_related_vesicles["lysosome-related vesicles"]
BORC -->|"phosphorylates"| AND["AND"]
BORC -->|"phosphorylates"| Oxidative_Phosphorylation["Oxidative Phosphorylation"]
BORC -->|"inhibits"| RNA["RNA"]| Target | Relation | Type | Str |
|---|---|---|---|
| Lysosome-Related Vesicle Transport | regulates | process | 0.95 |
| Lysosome-Related Vesicles | interacts_with | process | 0.95 |
| Mrna Transport | regulates | process | 0.95 |
| Axonal Mrna Depletion | causes | phenotype | 0.95 |
| Axonal mRNA Transport | mediates | process | 0.93 |
| Mitochondrial Proteins | regulates | protein | 0.90 |
| axonal mRNA transport | regulates | process | 0.70 |
| lysosome-related vesicles | interacts_with | cell_type | 0.70 |
| RNA | associated_with | gene | 0.60 |
| AXON | associated_with | gene | 0.60 |
| AND | phosphorylates | gene | 0.60 |
| NEURODEGENERATIVE DISORDERS | associated_with | gene | 0.60 |
| Oxidative Phosphorylation | phosphorylates | pathway | 0.60 |
| Stem Cell | associated_with | cell_type | 0.60 |
| Neuron | associated_with | cell_type | 0.60 |
| LYSOSOME | associated_with | gene | 0.60 |
| RNA | inhibits | gene | 0.60 |
| Oxidative Phosphorylation | inhibits | pathway | 0.60 |
| Stem Cell | transports | cell_type | 0.60 |
| Neuron | transports | cell_type | 0.60 |
| Kinesin | associated_with | protein | 0.60 |
| neurodegeneration | associated_with | disease | 0.60 |
| Stem Cell | expressed_in | cell_type | 0.55 |
| Neuron | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LYSOSOME | associated_with | gene | 0.60 |
| AXON | associated_with | gene | 0.60 |
| NEURODEGENERATIVE DISORDERS | associated_with | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity