BRCA2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolBRCA2
NameBRCA2 DNA repair associated
Typeprotein-coding
Sourcemygene

Summary

The product of this gene in involved in maintenance of genome stability. It is involved in double-strand break repair pathways during mitotic and meiotic homologous recombination and functions in protecting DNA replication forks. The encoded protein contains sites for interactions with PALB2 and EMSY and an N-terminal DNA binding domain. It also contains a RAD51 binding domain with multiple components. It has multiple BRC repeats, an alpha helix domain, oligonucleotide binding folds, and a tower

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