gene 654 words KG: BRCA2
Contents

BRCA2 Gene

🧬 Gene Info
Gene SymbolBRCA2
Full NameBRCA2 DNA Repair Associated
Chromosome13q13.1
FunctionThe BRCA2 gene encodes BRCA2 DNA Repair Associated, involved in DNA repair and genomic stability
Molecular Weight384 kDa
PathwaysAutophagy, Ferroptosis, Homologous Recombination, Innate Immunity, Oxidative Stress
UniProt IDBRCA2
NCBI Gene ID675
Ensembl IDENSG00000139618
OMIM600185
GeneCardsBRCA2
Human Protein AtlasBRCA2
DNA repairCritical for maintaining genomic integrity
Cell cycle regulationCoordinates DNA repair with cell cycle progression
[Apoptosis](/entities/apoptosis)Modulates apoptotic response to DNA damage
Associated DiseasesAls, Breast Cancer, Cancer, Carcinoma
InteractionsAPOPTOSIS, ATM, AUTOPHAGY, BRCA1, CANCER, CDKN2A
KG Connections160 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CD38 therapeutic_target BRCA2
FOXP1 therapeutic_target BRCA2
TERT therapeutic_target BRCA2
LC3 activates BRCA2
P62 activates BRCA2
TRIM25 activates BRCA2
SIRT6 regulates BRCA2
PARP1 regulates BRCA2
HNRNPA1 activates BRCA2
MYC regulates BRCA2

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