gene

C12ORF65

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about C12ORF65: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

C12orf65 - Mitochondrial Release Factor

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🧬 Gene Info

Gene Symbol	C12ORF65
Full Name	Chromosome 12 Open Reading Frame 65
Aliases	Page for C12orf65
Chromosome	12
Function	C12orf65 (also known as mitochondrial release factor) is a mitochondrial matrix protein that functions as a peptide release factor in mitochondrial translation termination.
UniProt ID	[Q5R390](https://www.uniprot.org/uniprot/Q5R390)
Ensembl ID	ENSG00000178732
GeneCards	C12ORF65
Human Protein Atlas	C12ORF65
Brain	Cerebral cortex, basal ganglia, brainstem
Retina	High expression in retinal ganglion cells
Skeletal muscle	High metabolic demand
Heart	Cardiac muscle
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

C12orf65 - Mitochondrial Release Factor

gene · 603 words

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Genes

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Pathway Diagram

graph TD
    C12ORF65["C12ORF65"]
    neurodegeneration["neurodegeneration"]
    C12ORF65 -->|"implicated_in"| neurodegeneration
    style C12ORF65 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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