Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about C1R/C1S: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Tnf-Α | activates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| TNF-α–C1r/C1s Bridge Between NF-κB and Classical Complement | 0.600 | neuroinflammation | How does sevoflurane-induced NF-κB activ |
| Therapeutic Repurposing: C1-INH as Plaque-Stabilizing Agent | 0.530 | neuroinflammation | What are the specific molecular mechanis |
Scientific analyses that reference this entity
neuroinflammation | 2026-04-08 | 5 hypotheses Top: 0.658
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning C1R/C1S in their description or question text
No additional research found