Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CAMK2B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | CAMK2B |
| Chromosome | 22q12.2 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 60 kDa |
| Amino Acids | 542 aa |
| Exons | 20 |
| GeneCards | CAMK2B |
| Human Protein Atlas | CAMK2B |
| AMPA receptor GluA1 | S831 |
| [NMDA](/entities/nmda-receptor) receptor NR2B | S1303 |
| Synapsin I | S566 |
| CREB | S133 |
| [Tau](/proteins/tau) | S262/356 |
| MAP2 | Multiple |
| Approach | Strategy |
| Associated Diseases | neurodegeneration |
| Interactions | PLCB3 |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CAMK2B["CAMK2B"]
neurodegeneration["neurodegeneration"]
CAMK2B -->|"implicated in"| neurodegeneration
PLCB3["PLCB3"]
PLCB3 -->|"interacts with"| CAMK2B
style CAMK2B fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| PLCB3 | interacts_with | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||