CDH1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCDH1
Namecadherin 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ov

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This is an externally resolved entity

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