Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CDK11: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | CDK11 |
| Full Name | Cyclin-Dependent Kinase 11 |
| Chromosome | 1p36.21 (CDK11A), 1p36.21 (CDK11B) |
| Protein Type | Kinase |
| Function | encodes a member of the cyclin-dependent kinase (CDK) family that includes two highly similar isoforms: CDK11A (also known as CDK11A) and CDK11B (also known as CDK11B). |
| Primary Expression | Brain, Testis, Lung, Ubiquitous |
| Molecular Weight | 110 kDa |
| Amino Acids | 795 aa |
| Exons | 20 |
| Pathways | MAPK pathway |
| UniProt ID | Q9UQ88 |
| Ensembl ID | ENSG00000049245 |
| GeneCards | CDK11 |
| Human Protein Atlas | CDK11 |
| Associated Diseases | Neuroblastoma, Lung Cancer, Various Cancers |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
CDK11["CDK11"]
neurodegeneration["neurodegeneration"]
CDK11 -->|"implicated_in"| neurodegeneration
style CDK11 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||