Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CEFTRIAXONE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CEFTRIAXONE |
| Summary | Ceftriaxone was evaluated in a large Phase 3 trial for ALS treatment based on its ability to upregulate the glutamate transporter GLT-1 |
| Key Genes/Proteins | GFAP, ALPHA_SYNUCLEIN |
| Related Diseases | ALEXANDER_DISEASE |
Knowledge base pages for this entity
graph TD
CEFTRIAXONE["CEFTRIAXONE"]
CEFTRIAXONE -->|"interacts"| GFAP["GFAP"]
CEFTRIAXONE -->|"inhibits"| GFAP_Aggregation["GFAP Aggregation"]
CEFTRIAXONE -->|"treats"| Alexander_s_Disease["Alexander's Disease"]
CEFTRIAXONE -->|"targets"| Blood_Brain_Barrier["Blood-Brain Barrier"]
CEFTRIAXONE -->|"inhibits"| Alpha_Synuclein_Aggregation["Alpha-Synuclein Aggregation"]| Target | Relation | Type | Str |
|---|---|---|---|
| GFAP | interacts_with | protein | 0.72 |
| ALEXANDER_DISEASE | treats | disease | 0.64 |
| ALPHA_SYNUCLEIN | inhibits | protein | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||