CHCHD10

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolCHCHD10
Namecoiled-coil-helix-coiled-coil-helix domain containing 10
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19. [provided by RefSeq, Aug 2014].

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