| Gene Symbol | CHCHD10 |
| Full Name | Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 10 |
| Aliases | CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 |
| Chromosome | 22q11.23 |
| Protein Family | CHCH domain-containing protein family |
| Function | Together they stabilize the mitochondrial contact site and cristae organizing system (MICOS), which maintains cristae morphology essential for efficient OXPHOS (Genin et al., 2016). |
| Primary Expression | Motor cortex, Spinal cord, Mitochondria (widespread) |
| Subcellular Localization | the mitochondrial intermembrane space (IMS), where it plays a role in maintaining cristae morphology and oxidative phosp |
| Molecular Weight | 14 kDa |
| Amino Acids | 182 aa |
| UniProt ID | Q8WYQ3 |
| Ensembl ID | ENSG00000250479 |
| GeneCards | CHCHD10 |
| Human Protein Atlas | CHCHD10 |
| Associated Diseases | Als, AMYOTROPHIC LATERAL SCLEROSIS, AUTOPHAGY, cardiovascular disease, frontotemporal dementia |
| Interactions | ALS, CCNF, CHCHD2, FTLD, FUS, GBA |
| KG Connections | 116 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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